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If you are taking any of these drugs: Isosorbide dinitrate, isosorbide mononitrate, nitroglycerin, riociguat, or ritonavir. If you are taking any of these drugs: Itraconazole or ketoconazole. If you are taking another drug that has the same drug in it. If you are taking another drug like this one that is used to treat erectile dysfunction (ED Can I Take Expired Sildenafil? Avoid taking sildenafil if it s expired. According to the FDA (U.S. Food and Drug Administration), this is why you should skip taking and safely dispose of expired meds: They might be less effective. They might be harboring bacteria (ew). Their chemical composition could be altered, making them unsafe. How can can you take expired sildenafil Usually any medication over 12 months old is considered expired in both prescription and in age. If the date on the pill bottle is more than 18 months past the fill date than the meds you have are more than likely expired. The risks of taking a medication that are out of date increase. The FDA isn t going to arrest you for taking expired Viagra. It may work, in which case, rock on. Or it may not work, and you ll end up getting some kind of tummy ache from yeast, which is probably also something you risk every day of your life anyway. To be clear, I m not recommending you take expired medications in any context. I m